Bissersheim has 450 inhabitants and an area of 2,6 km². It was first documentally mentioned in 774 as "Bizziricheshaim".

The protestant church of Saint Blaise and Margaret is a baroque nave style church built in 1755, the steeple is from the beginning of the 13th century, the baroque spire from 1776.

Bissersheim has several timbered houses from the 17th to 19th century.